What you need to know before planning a family.
Verelst Pharma “PREGNANCY SUPPORT” is designed to provide all essential ingredients in the exact composition to support maternal health and fetal development. Furthermore, our formulation completely bypasses MTHFR mutations, even homozygous MTHFR mutation (double mutation) will be bypassed and delivers the reduced folate immediately.
Using “PREGNANCY SUPPOR” 5-MTHF instead of folic acid reduces the potential for masking haematological symptoms of vitamin B12 deficiency, reduces interactions with medication that inhibit dihydrofolate reductase and overcomes metabolic defects caused by methylenetetrahydrofolate reductase polymorphism. Use of 5-MTHF also prevents the potential negative effects of unconverted folic acid in the peripheral circulation. Furthermore, our formulation uses the direct bio-available Methylcobalamin (active B12) and Pyridoxal-5-Phosphate (active B6).
Folic acid is recognized as a major component of the periconceptionally care of women in the reproductive age group. Deficiency of folic acid can lead to neural tube defects in the foetus and megaloblastic anaemia in the mother.
Only in recent years have they learned of the link between folic acid and the inefficiency to be mobilized to the bio-available methyl folate. Furthermore, recent studies show that supplementation from 4 weeks before conception to 8 weeks thereafter is proven to be inefficient. New guidelines advice at least 3 months before conception and throughout pregnancy and lactation.
About half of the world population appears to have a gene mutation on the gene coding for the production of MTHFR (methylenetetrahydrofolate reductase), the enzyme that is involved in the formation of 5-MTHF (5-methyltetrahydrofolate) which is, in his turn, responsible for the conversion of the toxic homocysteine in methionine. Women with such a gene polymorphism have a significantly higher risk to have a miscarriage or a baby with neural tube defects.
In contrast, folic acid cannot directly be used by the body. It must be converted by two chemical reactions into another folate that your body can metabolize—specifically, MTHF folate. Indeed, folic acid must first be converted into MTHF folate for your body to use it. Supplemental folic acid also carries the risk of masking symptoms of B12 deficiency, which can lead to anaemia, one of the very risks you’re trying to prevent by taking a prenatal vitamin.